European Network of Investigators Triggering Exploratory Research on Myeloid Regulatory Cells (Mye-EUNITER)

Project Status: 
Ongoing
Project type: 
Cost action
Project Identification Number: 
BM1404
Date Project Started: 
November, 2014
Date Project Ended: 
November, 2018
Total funding of project (Euro): 
N/A
Total funding to IUS Budget (Euro): 
N/A
Funding organization / government / company: 
EU commission
Project Description: 
In cancer, infection and inflammation, the immune system’s function can be dysregulated, contributing to disease pathology. As part of this process, instead of fighting disease, immune cells may suppress beneficial immune responses and increase pathology. Despite their pathophysiological importance, the identity and biology of the so called myeloid regulatory cells (MRCs) is poorly understood. Depending on the MRC subtype and the respective disease, conflicting results have been published. This Action will form a network of researchers and clinicians which aims to establish a gold standard of common protocols and harmonizing guidelines for the analysis and clinical monitoring of MRCs. There is also a deficit in the translation of findings from animal models to humans, and Mye-EUNITER will build an analytical mouse-monkey-man correlation line. Standardized and validated tools for MRC analysis will aid the development of cellular biomarkers of disease and guide the design of novel therapies to manipulate the functions of MRCs.
IUS Participant(s): 
Name & SurnameRoleFacultyStudy Programme
Participant
Faculty of Engineering and Natural Sciences
Genetics and Bioengineering